Understanding Cholesterol
Cholesterol is a type of fat (lipid) produced in small quantities
by the liver and contained in many of the foods we commonly eat
including fried foods, butter, cheese products, and red meats. Cholesterol
does not dissolve in our blood stream and it attaches to the insides
of the arteries supplying blood to the muscle of the heart, the
brain and the extremities. These deposits of cholesterol initiate
a physiological process leading to narrowing of the arteries. Doctors
call this process arteriosclerosis.
Arteriosclerosis may develop in any artery in our body, but doctors
become most concerned when arteriosclerosis injures the arteries
supplying blood to our heart muscle (coronary arteries), the arteries
supplying blood to our brain (carotid arteries) or the arteries
supplying blood to our feet and legs (peripheral arteries).
Sometimes clots may suddenly occlude arteries already narrowed
and damaged by arteriosclerosis. When a clot suddenly occludes an
artery supplying blood to the muscle of the heart, patients experience
a heart attack. Similarly the sudden cessation of blood flow to
the brain results in a stroke.
Arteries damaged by arteriosclerosis may also narrow slowly. In
the case of the coronary arteries (heart) this gradual narrowing
will cause intermittent chest pain known as angina. In the case
of peripheral arteries supplying blood to the legs and feet, this
gradual narrowing will cause pain with walking called claudication.
Monitoring and lowering levels of cholesterol in the blood will
decrease your risk of a heart attack, stroke or claudication. In
order to better achieve this goal, doctors divide cholesterol into
two major categories: low density lipoproteins and high-density
lipoproteins (HDL). Low-density lipoproteins (LDL) describe the
microscopic packages of cholesterol wrapped in proteins traveling
from the liver and gastrointestinal system to the susceptible arteries.
High-density lipoproteins describe the microscopic packages of cholesterol
wrapped in proteins carrying the cholesterol away from the susceptible
arteries. The goal of cholesterol treatment is to decrease the quantity
of LDL and increase the levels of HDL; thereby minimizing the amount
of cholesterol being deposited in the arteries and maximizing the
amount of cholesterol being removed from damaged arteries.
No matter what your medical circumstances, your HDL (high density
lipoproteins) should be greater than 40 mg/dl and your LDL (low
density lipoproteins) should be less than 160 mg/dl. If you smoke,
suffer from diabetes or come from a family with a tendency towards
heart disease, the cardiologist will try to lower your LDL below
130 mg/dl and if you recently suffered a heart attack most experts
recommend keeping your LDL below 100 mg/dl.
If necessary our cardiologists will initiate treatment with dietary
recommendations and an exercise program. If the LDL level remains
elevated after these measures, most cardiologists will begin medication.
Modern medicine offers a large variety of potential cholesterol
lowering medications including Lipitor, Zocor,
Pravachol, niacin and others. Which medication the cardiologist
selects depends on your blood test results, coexisting medical illnesses
and other unique circumstances.
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